Chemical Reagents for Protein Modification, Fourth Edition - download pdf or read online

By Roger L. Lundblad

The use of the chemical amendment of proteins has advanced during the last eighty years, profiting from advances in analytical, actual, and natural chemistry. during the last 30 years, using chemical reagents to change proteins has been an important in settling on the functionality and constitution of purified proteins. This groundbreaking paintings is a part of the root of rising disciplines of proteomics, chemical biology, constitution biology, and chemical proteomics.

Chemical Reagents for Protein amendment, Fourth Edition offers a accomplished overview of reagents used for the chemical amendment of proteins, representing a tremendous revision of the paintings awarded in prior versions. The thoroughly up-to-date Fourth version is considerably greater and comprises 5 new chapters:




  • Alkylating Agents

  • Acylating Agents

  • Nitration and Nitrosylation

  • Oxidation

  • Modification of Proteins with lowering Agents


There is enormously elevated insurance of the chemical amendment of cysteine, that's severe for bioconjugate synthesis. The bankruptcy on relief additionally presents details invaluable for bioconjugate synthesis in addition to for the processing of inclusion our bodies. The e-book areas emphasis on stipulations that impact the specificity of the chemical amendment of proteins, reminiscent of solvent and temperature. The structure has been markedly revised, providing info in accordance with the chemical nature of the editing fabric and at the amino acid residue converted. This new edition has elevated importance to biopharmaceuticals. a lot of the data is in tabular shape, which allows the quick situation of stated material.

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Chemical Reagents for Protein Modification, Fourth Edition by Roger L. Lundblad


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