Download PDF by Robert Doran: Asymmetric Synthesis of Bioactive Lactones and the

By Robert Doran

This thesis addresses basic components in modern natural chemistry: synthesis of usual items and catalytic uneven synthesis. first of all, a brand new method, constructed by way of our learn workforce, which permits the uneven synthesis of lactones, a structural unit ubiquitous in usual items, was once utilised within the synthesis of a couple of common product analogues that confirmed major organic task. Secondly, the improvement of a catalytic uneven synthesis of a key structural motif found in a couple of average items and prescribed drugs used to be entire. in the course of the process this paintings we came across twin stereo keep an eye on, that's major since it permits the configuration of a brand new stereo centre to be managed by way of an easy swap of proton source.

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Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of α-Aryl Ketones (Springer Theses) by Robert Doran


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