Get Analysis of Complex Diseases: A Mathematical Perspective PDF

By Guanyu Wang PhD

A complicated disorder includes many etiological and threat elements working at a number of levels—molecular, mobile, organismal, and environmental. The prevalence of such illnesses as melanoma, weight problems, and diabetes are expanding in prevalence, urging us to imagine essentially and use a broader standpoint to spot their connection and revolutionize remedies. the knowledge of organic facts derived from learning illnesses will be improved via theories and mathematical versions, which make clear the massive photo and aid to bare the overarching mechanisms that govern complicated organic phenomena.

Focusing on ailments relating to mobile strength metabolism, equivalent to melanoma and diabetes, Analysis of complicated illnesses: A Mathematical Perspective offers a holistic procedure for illuminating the molecular mechanisms of those illnesses and the evolutionary underpinning in their simultaneous epidemics. utilizing arithmetic to spot styles of deviation from normality, or the fit state—spanning a number of degrees from molecules to the organism—the writer identifies more than a few dynamical behaviors that correspond to both mobile body structure or pathology. He makes use of the data from a number of degrees that allows you to advance a unified conception, along with the invention that definite ailments may well stem from well-evolved, beneficial mechanisms activated within the incorrect context.

This e-book is split into 3 components. half I specializes in the organismal point to explain general body structure and the way the physique as a complete meets its sensible necessities. half II addresses the subcellular, molecular point to explain the organizing ideas of mobile biomolecules to satisfy the calls for of the organism. half III examines complicated illnesses by means of combining info from the organismal point and the molecular point, delivering a paradigm that may be prolonged to the examine of different different types of ailments.

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Analysis of Complex Diseases: A Mathematical Perspective by Guanyu Wang PhD

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